| Luna Buijtenhuijs (RGV) def. Laia Tarazona Peyro (UTSA) 5-7, 6-3, 6-4 |
| Juana Gomez Weiss (RGV) def. Marissa Minetti (TSU) 6-3, 6-4 |
| Elena Mireles (SMU) def. Rhea Makesar (RGV) 6-2, 6-2 |
| Rhea Makesar (RGV) def. Aruzhan Nuranbay (TSU) 6-3, 6-3 |
| Juana Gomez Weiss (RGV) def. Kenna Erickson (BU) walkover |
| Hitakamya Narwal (RGV) def. Erika Abraham-Nilsen (TSU) 6-1, 6-4 |
| Alexia Puiac (UH) def. Mariangel Estrella (RGV) 6-1, 2-6, 6-2 |
| Vlada Razina (UH) def. Mirka Delaney (RGV) 6-0, 6-3 |
| Rhea Makesar (RGV) def. Anna Huisgen (TSU) 4-6, 7-5, 6-4 |
| Yoana Konstantinova (TAMU) def. Hitakamya Narwal (RGV) 6-3, 6-3 |
| Diana Khaydarshina (UTSA) def. Madeleine Joffe (RGV) 6-1, 6-1 |
| Nithesa Selvaraj (RICE) def. Mariangel Estrella (RGV) 3-6, 6-4, 6-1 |
| Juana Gomez Weiss (RGV) def. Marie Krymlova (AMCC) 6-3, 6-4 |
| Sofiia Mykhailets (TCU) def. Hitakamya Narwal (RGV) 6-2, 6-2 |
| Rhea Makesar (RGV) def. Julia Ionescu (ACU) 6-2, 6-4 |
| Kseniya Ramanouskaya (AMCC) def. Juana Gomez Weiss (RGV) 6-1, 6-4 |
| Maguina Bunikowska (RICE) def. Luna Buijtenhuijs (RGV) 6-2, 3-0, retired |
| Anna Krljic (ACU) def. Hitakamya Narwal (RGV) 6-4, 6-3 |
| Alem Cote (ACU) def. Mirka Delaney (RGV) 4-6, 6-1, 1-0 (10-7) |
| Maria Isabel Suarez (UTA) def. Madeleine Joffe (RGV) 4-6, 7-6 (7-2), 1-0 (10-2) |
